Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel

Patrick Dansette; Stéphanie Thébault; Gildas Bertho; Daniel Mansuy

doi:10.1021/tx1001332

Journal articles

Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel

Patrick Dansette ^{1, 2} Stéphanie Thébault Gildas Bertho ¹ Daniel Mansuy ^{1, 2}

1 UPD5 - Université Paris Descartes - Paris 5

2 LCBPT - UMR 8601 - Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques

Document type :

Journal articles

Domain :

Life Sciences [q-bio]

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https://hal-univ-paris.archives-ouvertes.fr/hal-03684983
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Submitted on : Wednesday, June 1, 2022 - 5:31:00 PM
Last modification on : Saturday, June 25, 2022 - 3:43:28 AM

Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel

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Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel

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