Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel

Patrick Dansette; Stéphanie Thébault; Gildas Bertho; Daniel Mansuy

doi:10.1021/tx1001332

Journal Articles Chemical Research in Toxicology Year : 2010

Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel

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1
2

Patrick Dansette

Function : Author

Université Paris Descartes - Paris 5

Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques

Stéphanie Thébault

Function : Author

Gildas Bertho

Function : Author
PersonId : 178255
IdHAL : gildas-bertho
ORCID : 0000-0002-4929-763X
IdRef : 149617593

Université Paris Descartes - Paris 5

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Daniel Mansuy

Function : Author
PersonId : 756474
IdRef : 132533553

Université Paris Descartes - Paris 5

Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques

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Life Sciences [q-bio]

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https://hal-univ-paris.archives-ouvertes.fr/hal-03684983

Submitted on : Wednesday, June 1, 2022-5:31:00 PM

Last modification on : Saturday, June 25, 2022-3:43:28 AM

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hal-03684983 , version 1 (01-06-2022)

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HAL Id : hal-03684983 , version 1
DOI : 10.1021/tx1001332

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Patrick Dansette, Stéphanie Thébault, Gildas Bertho, Daniel Mansuy. Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel. Chemical Research in Toxicology, 2010, 23 (7), pp.1268-1274. ⟨10.1021/tx1001332⟩. ⟨hal-03684983⟩

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Formation and Fate of a Sulfenic Acid Intermediate in the Metabolic Activation of the Antithrombotic Prodrug Prasugrel

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