Impact of positive charge and ring-size on the interactions of calixarenes with DNA, RNA and nucleotides

Ivona Krošl , Ena Otković , Ivana Nikšić-Franjić , Benoit Colasson , Olivia Reinaud (1, 2) , Aleksandar Višnjevac , Ivo Piantanida

1 LCBPT - UMR 8601 - Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques
2 UPCité - Université Paris Cité

Cationic calix[6]arene and calix[4]arene derivatives non-covalently bind into a DNA minor groove or RNA major groove and form tweezer-like complexes with nucleotides.

Domains: Chemical Sciences

Ivona Krošl, Ena Otković, Ivana Nikšić-Franjić, Benoit Colasson, Olivia Reinaud, et al.. Impact of positive charge and ring-size on the interactions of calixarenes with DNA, RNA and nucleotides. New Journal of Chemistry, 2022, 46 (15), pp.6860-6869. ⟨10.1039/D2NJ00061J⟩. ⟨hal-03726494⟩