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Cytochromes P450 Catalyze Both Steps of the Major Pathway of Clopidogrel Bioactivation, whereas Paraoxonase Catalyzes the Formation of a Minor Thiol Metabolite Isomer

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https://hal-univ-paris.archives-ouvertes.fr/hal-03684944
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Submitted on : Wednesday, June 1, 2022 - 5:08:40 PM
Last modification on : Saturday, June 25, 2022 - 3:43:26 AM

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Patrick Dansette, Julien Rosi, Gildas Bertho, Daniel Mansuy. Cytochromes P450 Catalyze Both Steps of the Major Pathway of Clopidogrel Bioactivation, whereas Paraoxonase Catalyzes the Formation of a Minor Thiol Metabolite Isomer. Chemical Research in Toxicology, American Chemical Society, 2012, 25 (2), pp.348-356. ⟨10.1021/tx2004085⟩. ⟨hal-03684944⟩

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