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Thiolactone Sulfoxides as New Reactive Metabolites Acting as Bis-Electrophiles: Implication in Clopidogrel and Prasugrel Bioactivation

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https://hal-univ-paris.archives-ouvertes.fr/hal-03684856
Contributor : Gildas BERTHO Connect in order to contact the contributor
Submitted on : Wednesday, June 1, 2022 - 4:36:10 PM
Last modification on : Saturday, June 25, 2022 - 3:43:29 AM

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Patrick Dansette, Dan Levent, Assia Hessani, Gildas Bertho, Daniel Mansuy. Thiolactone Sulfoxides as New Reactive Metabolites Acting as Bis-Electrophiles: Implication in Clopidogrel and Prasugrel Bioactivation. Chemical Research in Toxicology, American Chemical Society, 2013, 26 (5), pp.794-802. ⟨10.1021/tx400083b⟩. ⟨hal-03684856⟩

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