Skip to Main content Skip to Navigation
Journal articles

Carotid Ultrasound Boundary Study (CUBS): An Open Multicenter Analysis of Computerized Intima–Media Thickness Measurement Systems and Their Clinical Impact

Abstract : Common carotid intimaÀmedia thickness (CIMT) is a commonly used marker for atherosclerosis and is often computed in carotid ultrasound images. An analysis of different computerized techniques for CIMT measurement and their clinical impacts on the same patient data set is lacking. Here we compared and assessed five computerized CIMT algorithms against three expert analysts' manual measurements on a data set of 1088 patients from two centers. Inter-and intra-observer variability was assessed, and the computerized CIMT values were compared with those manually obtained. The CIMT measurements were used to assess the correlation with clinical parameters, cardiovascular event prediction through a generalized linear model and the KaplanÀMeier hazard ratio. CIMT measurements obtained with a skilled analyst's segmentation and the computerized segmentation were comparable in statistical analyses, suggesting they can be used interchangeably for CIMT quantification and clinical outcome investigation. To facilitate future studies, the entire data set used is made publicly
Document type :
Journal articles
Complete list of metadata

https://hal-univ-paris.archives-ouvertes.fr/hal-03254420
Contributor : Equipe Hal Université de Paris Connect in order to contact the contributor
Submitted on : Tuesday, June 8, 2021 - 5:48:16 PM
Last modification on : Tuesday, October 19, 2021 - 11:40:53 AM
Long-term archiving on: : Thursday, September 9, 2021 - 8:26:53 PM

File

PIIS0301562921001411.pdf
Publisher files allowed on an open archive

Licence


Distributed under a Creative Commons Attribution - NonCommercial - NoDerivatives 4.0 International License

Identifiers

Collections

Citation

Kristen Meiburger, Guillaume Zahnd, Francesco Faita, Christos Loizou, Catarina Carvalho, et al.. Carotid Ultrasound Boundary Study (CUBS): An Open Multicenter Analysis of Computerized Intima–Media Thickness Measurement Systems and Their Clinical Impact. Ultrasound in Medicine & Biology, Elsevier, 2021, ⟨10.17632/fpv535fss7.1.⟩. ⟨hal-03254420⟩

Share

Metrics

Record views

18

Files downloads

31