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Environmental contaminants and child’s growth

Abstract : Experimental data have suggested that some contaminants in the environment may increase the risk of obesity. Infants can be exposed to chemicals either prenatally, by trans-placental passage of chemicals, or postnatally by their own diet and by other external pathways (air inhalation, dust, hand-to-mouth exposure) after birth. In order to provide a review of epidemiological evidence on the association between prenatal exposure to chemicals and prenatal and postnatal growth, we present the literature from systematic review articles and international meta-analyses, when available, or recent research articles when summarising articles were not available. The most studied contaminants in this field were persistent organic pollutants (e.g. organochlorinated pesticides, polychlorinated biphenyls, PCBs), non-persistent pollutants (e.g. phthalates, BPA), toxic heavy metals (i.e. cadmium, lead and mercury), arsenic, mycotoxins and acrylamide. Mounting evidence suggests that child’s growth may be associated with prenatal or postnatal exposures to environmental contaminants. Improving exposure assessment and studying the contaminants as mixtures should allow to gain knowledge about the environmental determinants of growth and obesity.
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https://hal.inrae.fr/hal-02904542
Contributor : Blandine de Lauzon-Guillain <>
Submitted on : Wednesday, July 22, 2020 - 12:23:42 PM
Last modification on : Tuesday, March 2, 2021 - 2:48:13 PM
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Manik Kadawathagedara, Blandine de Lauzon-Guillain, Jérémie Botton. Environmental contaminants and child’s growth. Journal of Developmental Origins of Health and Disease, Cambridge University Press, 2018, 9 (6), pp.632-641. ⟨10.1017/S2040174418000995⟩. ⟨hal-02904542⟩

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